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Heritable Stochastic Switching Revealed by Single-Cell Genealogy

The partitioning and subsequent inheritance of cellular factors like proteins and RNAs is a ubiquitous feature of cell division. However, direct quantitative measures of how such nongenetic inheritance affects subsequent changes in gene expression have been lacking. We tracked families of the yeast...

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Detalhes bibliográficos
Main Authors: Kaufmann, Benjamin B, Yang, Qiong, Mettetal, Jerome T, van Oudenaarden, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964776/
https://ncbi.nlm.nih.gov/pubmed/17803359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050239
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