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Transcript counting in single cells reveals dynamics of rDNA transcription

Most eukaryotes contain many tandem repeats of ribosomal RNA genes of which only a subset is transcribed at any given time. Current biochemical methods allow for the determination of the fraction of transcribing repeats (ON) versus non-transcribing repeats (OFF) but do not provide any dynamical info...

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Autors principals: Tan, Rui Zhen, van Oudenaarden, Alexander
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872610/
https://ncbi.nlm.nih.gov/pubmed/20393578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.14
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