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Predicting stochastic gene expression dynamics in single cells

Fluctuations in protein numbers (noise) due to inherent stochastic effects in single cells can have large effects on the dynamic behavior of gene regulatory networks. Although deterministic models can predict the average network behavior, they fail to incorporate the stochasticity characteristic of...

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Bibliografiske detaljer
Main Authors: Mettetal, Jerome T., Muzzey, Dale, Pedraza, Juan M., Ozbudak, Ertugrul M., van Oudenaarden, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464336/
https://ncbi.nlm.nih.gov/pubmed/16648266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509874103
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