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Single-Molecule Approaches to Stochastic Gene Expression

Both the transcription of mRNAs from genes and their subsequent translation into proteins are inherently stochastic biochemical events, and this randomness can lead to substantial cell-to-cell variability in mRNA and protein numbers in otherwise identical cells. Recently, a number of studies have gr...

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Detalhes bibliográficos
Main Authors: Raj, Arjun, van Oudenaarden, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126657/
https://ncbi.nlm.nih.gov/pubmed/19416069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.biophys.37.032807.125928
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