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Variability in gene expression underlies incomplete penetrance

The phenotypic differences between individual organisms can often be ascribed to underlying genetic and environmental variation. However, even genetically identical organisms in homogenous environments vary, suggesting that randomness in developmental processes such as gene expression may also gener...

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Bibliographic Details
Main Authors: Raj, Arjun, Rifkin, Scott A., Andersen, Erik, van Oudenaarden, Alexander
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836165/
https://ncbi.nlm.nih.gov/pubmed/20164922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08781
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