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Variability in Gene Expression is Associated with Incomplete Penetrance in Inherited Eye Disorders

Inherited eye disorders (IED) are a heterogeneous group of Mendelian conditions that are associated with visual impairment. Although these disorders often exhibit incomplete penetrance and variable expressivity, the scale and mechanisms of these phenomena remain largely unknown. Here, we utilize pub...

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Bibliographische Detailangaben
Veröffentlicht in:Genes (Basel)
Hauptverfasser: Green, David J., Sallah, Shalaw R., Ellingford, Jamie M., Lovell, Simon C., Sergouniotis, Panagiotis I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074066/
https://ncbi.nlm.nih.gov/pubmed/32050448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11020179
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