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ATP sensitivity of ATP-sensitive K(+) channels: role of the γ phosphate group of ATP and the R50 residue of mouse Kir6.2
ATP-sensitive K (K(ATP)) channels are composed of Kir6, the pore-forming protein, and the sulphonylurea receptor SUR, a regulatory protein. We and others have previously shown that positively charged residues in the C terminus of Kir6.2, including R201 and K185, interact with the α and β phosphate g...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1464185/ https://ncbi.nlm.nih.gov/pubmed/16166157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.095638 |
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