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ATP-sensitive K(+) channels: regulation of bursting by the sulphonylurea receptor, PIP(2) and regions of Kir6.2
ATP-sensitive K(+) channels composed of the pore-forming protein Kir6.2 and the sulphonylurea receptor SUR1 are inhibited by ATP and activated by Phosphatidylinositol Bisphosphate (PIP(2)). Residues involved in binding of these ligands to the Kir6.2 cytoplasmic domain have been identified, and it ha...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1796795/ https://ncbi.nlm.nih.gov/pubmed/16373383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.100719 |
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