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ATP sensitivity of ATP-sensitive K(+) channels: role of the γ phosphate group of ATP and the R50 residue of mouse Kir6.2

ATP-sensitive K (K(ATP)) channels are composed of Kir6, the pore-forming protein, and the sulphonylurea receptor SUR, a regulatory protein. We and others have previously shown that positively charged residues in the C terminus of Kir6.2, including R201 and K185, interact with the α and β phosphate g...

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Detalhes bibliográficos
Main Authors: John, Scott A, Weiss, James N, Ribalet, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464185/
https://ncbi.nlm.nih.gov/pubmed/16166157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.095638
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