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Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells
Sterol synthesis is required for Sonic hedgehog (Shh) signal transduction. Errors in Shh signal transduction play important roles in the formation of human tumors, including medulloblastoma (MB). It is not clear which products of sterol synthesis are necessary for Shh signal transduction or how they...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1462959/ https://ncbi.nlm.nih.gov/pubmed/16707575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602852103 |
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