Effects of oligonucleotide length, mismatches and mRNA levels on C-5 propyne-modified antisense potency.

To understand the parameters required for designing potent and specific antisense C-5 propynyl-pyrimidine-2'-deoxyphosphorothioate-modified oligonucleotides (C-5 propyne ONs), we have utilized a HeLa line that stably expresses luciferase under tight control of a tetracycline-responsive promoter. Usi...

Descrición completa

Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Principais autores:	Flanagan, W M, Kothavale, A, Wagner, R W
Formato:	Artigo
Idioma:	Inglês
Publicado:	Oxford University Press 1996
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146034/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8760877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.15.2936
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!