Effects of oligonucleotide length, mismatches and mRNA levels on C-5 propyne-modified antisense potency.
To understand the parameters required for designing potent and specific antisense C-5 propynyl-pyrimidine-2'-deoxyphosphorothioate-modified oligonucleotides (C-5 propyne ONs), we have utilized a HeLa line that stably expresses luciferase under tight control of a tetracycline-responsive promoter. Usi...
Na minha lista:
| Publicado no: | Nucleic Acids Res |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1996
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146034/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8760877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.15.2936 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|