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A Novel Mutation of STK11/LKB1 Gene Leads to the Loss of Cell Growth Inhibition in Head and Neck Squamous Cell Carcinoma
To investigate whether genetic alteration of the STK11/LKB1 tumor-suppressor gene is involved in the carcinogenesis of head and neck squamous cell carcinoma (HNSCC), the entire encoding exons and flanking intronic sequences of the STK11/LKB1 gene were analyzed with direct genomic sequencing of fifte...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1459486/ https://ncbi.nlm.nih.gov/pubmed/16407837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209325 |
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