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Disruption of Transforming Growth Factor β-Smad Signaling Pathway in Head and Neck Squamous Cell Carcinoma as Evidenced by Mutations of SMAD2 and SMAD4(1)
The role of the TGF-β-Smad signaling pathway in the carcinogenesis of head and neck cancer has not been fully evaluated genetically. In this study, we screened for mutation in the five main members of the TGF-β-Smad signaling pathway, TGF-β type I receptor (TGFBRI), TGF-β type II receptor (TGFBRII),...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1741856/ https://ncbi.nlm.nih.gov/pubmed/16478646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2006.01.003 |
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