טוען...
Electron microscopic structure of purified, active γ-secretase reveals an aqueous intramembrane chamber and two pores
γ-Secretase is an intramembrane-cleaving aspartyl protease required for the normal development of metazoans because it processes Notch within cellular membranes to release its signaling domain. More than two dozen additional substrates of diverse functions have been reported, including the Notch lig...
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| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2006
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458989/ https://ncbi.nlm.nih.gov/pubmed/16636269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602321103 |
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