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Structural and Functional Determinants of γ-Secretase, an Intramembrane Protease Implicated in Alzheimer’s Disease

Alzheimer’s disease is the most common form of neurodegenerative diseases in humans, characterized by the progressive accumulation and aggregation of amyloid-β peptides (Aβ) in brain regions subserving memory and cognition. These 39-43 amino acids long peptides are generated by the sequential proteo...

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Sonraí Bibleagrafaíochta
Príomhúdar: Fraering, Patrick C
Formáid: Artigo
Teanga:Inglês
Foilsithe: Bentham Science Publishers Ltd. 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647162/
https://ncbi.nlm.nih.gov/pubmed/19415127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920207783769521
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