Processing of the Synaptic Cell Adhesion Molecule Neurexin-3β by Alzheimer Disease α- and γ-Secretases

Neurexins (NRXNs) are synaptic cell adhesion molecules having essential roles in the assembly and maturation of synapses into fully functional units. Immunocytochemical and electrophysiological studies have shown that specific binding across the synaptic cleft of the ectodomains of presynaptic NRXNs...

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Bibliografiske detaljer
Main Authors: Bot, Nathalie, Schweizer, Claude, Ben Halima, Saoussen, Fraering, Patrick C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Neurobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024772/
https://ncbi.nlm.nih.gov/pubmed/21084300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142521
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