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Processing of the Synaptic Cell Adhesion Molecule Neurexin-3β by Alzheimer Disease α- and γ-Secretases

Neurexins (NRXNs) are synaptic cell adhesion molecules having essential roles in the assembly and maturation of synapses into fully functional units. Immunocytochemical and electrophysiological studies have shown that specific binding across the synaptic cleft of the ectodomains of presynaptic NRXNs...

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Détails bibliographiques
Auteurs principaux: Bot, Nathalie, Schweizer, Claude, Ben Halima, Saoussen, Fraering, Patrick C.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024772/
https://ncbi.nlm.nih.gov/pubmed/21084300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142521
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