Processing of the Synaptic Cell Adhesion Molecule Neurexin-3β by Alzheimer Disease α- and γ-Secretases

Neurexins (NRXNs) are synaptic cell adhesion molecules having essential roles in the assembly and maturation of synapses into fully functional units. Immunocytochemical and electrophysiological studies have shown that specific binding across the synaptic cleft of the ectodomains of presynaptic NRXNs...

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Autors principals: Bot, Nathalie, Schweizer, Claude, Ben Halima, Saoussen, Fraering, Patrick C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Neurobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024772/
https://ncbi.nlm.nih.gov/pubmed/21084300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142521
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