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Recent developments of small molecule γ-secretase modulators for Alzheimer's disease

Alzheimer's disease (AD) is the most common form of progressive neurodegenerative disorder, marked by memory loss and a decline in cognitive function. The major hallmarks of AD are the presence of intracellular neurofibrillary tau tangles (NFTs) composed of hyperphosphorylated tau proteins and...

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Detalhes bibliográficos
Publicado no:RSC Med Chem
Main Authors: Mekala, Shekar, Nelson, Grady, Li, Yue-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513388/
https://ncbi.nlm.nih.gov/pubmed/33479693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00196a
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