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An l-RNA-based aquaretic agent that inhibits vasopressin in vivo
A class of diuretic/aquaretic agents based on mirror-image oligonucleotides (so-called Spiegelmers) has been identified. These molecules directly bind and inhibit the neuropeptide vasopressin (AVP). AVP is the major regulatory component of body fluid homeostasis mediated through binding to the renal...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458813/ https://ncbi.nlm.nih.gov/pubmed/16547136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509663103 |
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