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Development of an automated in vitro selection protocol to obtain RNA-based aptamers: identification of a biostable substance P antagonist

We have developed an automated SELEX (Systematic Evolution of Ligands by EXponential Enrichment) process that allows the execution of in vitro selection cycles without any direct manual intervention steps. The automated selection protocol is designed to provide for high flexibility and versatility i...

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Detalhes bibliográficos
Main Authors: Eulberg, Dirk, Buchner, Klaus, Maasch, Christian, Klussmann, Sven
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC552970/
https://ncbi.nlm.nih.gov/pubmed/15745995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni044
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