Biostable aptamers with antagonistic properties to the neuropeptide nociceptin/orphanin FQ

The neuropeptide nociceptin/orphanin FQ (N/OFQ), the endogenous ligand of the opioid receptor-like 1 (ORL1) receptor, has been shown to play a prominent role in the regulation of several biological functions such as pain and stress. Here we describe the isolation and characterization of N/OFQ bindin...

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Main Authors: FAULHAMMER, DIRK, ESCHGFÄLLER, BERND, STARK, SANDRA, BURGSTALLER, PETRA, ENGLBERGER, WERNER, ERFURTH, JEANNETTE, KLEINJUNG, FRANK, RUPP, JOHANNA, VULCU, SEBASTIAN DAN, SCHRÖDER, WERNER, VONHOFF, STEFAN, NAWRATH, HERMANN, GILLEN, CLEMENS, KLUSSMANN, SVEN
Format: Artigo
Sprog:Inglês
Udgivet: Copyright 2004 by RNA Society 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370946/
https://ncbi.nlm.nih.gov/pubmed/14970396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5186504
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