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Stimulation of sensory neuropeptide release by nociceptin/orphanin FQ leads to hyperaemia in acutely inflamed rat knees

1. The peripheral effect of the ‘opioid-like' peptide nociceptin/orphanin FQ (N/OFQ) on joint blood flow was investigated in acutely inflamed rats. Sensory neuropeptide release from capsaicin-sensitive nerves and the involvement of synovial mast cells and leukocytes on these vasomotor responses...

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Detalhes bibliográficos
Main Authors: Zhang, Chunfen, McDougall, Jason J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751929/
https://ncbi.nlm.nih.gov/pubmed/16783411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706804
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