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Polyetheylenimine-Polyplexes of Spiegelmer NOX-A50 Directed against Intracellular High Mobility Group Protein A1 (HMGA1) Reduce Tumor Growth in Vivo

High mobility group A1 (HMGA1) proteins belong to a group of architectural transcription factors that are overexpressed in a range of human malignancies, including pancreatic adenocarcinoma. They promote anchorage-independent growth and epithelial-mesenchymal transition and are therefore suggested a...

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Detalhes bibliográficos
Main Authors: Maasch, Christian, Vater, Axel, Buchner, Klaus, Purschke, Werner G., Eulberg, Dirk, Vonhoff, Stefan, Klussmann, Sven
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000983/
https://ncbi.nlm.nih.gov/pubmed/20961861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178533
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