The effects of the anti-hepcidin Spiegelmer NOX-H94 on inflammation-induced anemia in cynomolgus monkeys

Anemia of chronic inflammation is the most prevalent form of anemia in hospitalized patients. A hallmark of this disease is the intracellular sequestration of iron. This is a consequence of hepcidin-induced internalization and subsequent degradation of ferroportin, the hepcidin receptor and only kno...

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Autors principals: Schwoebel, Frank, van Eijk, Lucas T., Zboralski, Dirk, Sell, Simone, Buchner, Klaus, Maasch, Christian, Purschke, Werner G., Humphrey, Martin, Zöllner, Stefan, Eulberg, Dirk, Morich, Frank, Pickkers, Peter, Klussmann, Sven
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2013
Matèries:
Red Cells, Iron, and Erythropoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606066/
https://ncbi.nlm.nih.gov/pubmed/23349391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-09-456756
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