Randomized double-blind placebo-controlled PK/PD study on the effects of a single intravenous dose of the anti-hepcidin Spiegelmer NOX-H94 on serum iron during experimental human endotoxemia

Eitemau Tebyg

• Safety, pharmacokinetics and pharmacodynamics of the anti‐hepcidin Spiegelmer lexaptepid pegol in healthy subjects
  gan: Boyce, M, et al.
  Cyhoeddwyd: (2016)
• The effects of the anti-hepcidin Spiegelmer NOX-H94 on inflammation-induced anemia in cynomolgus monkeys
  gan: Schwoebel, Frank, et al.
  Cyhoeddwyd: (2013)
• Effect of the antihepcidin Spiegelmer lexaptepid on inflammation-induced decrease in serum iron in humans
  gan: van Eijk, Lucas T., et al.
  Cyhoeddwyd: (2014)
• Hypoxia attenuates inflammation-induced hepcidin synthesis during experimental human endotoxemia
  gan: Kiers, Dorien, et al.
  Cyhoeddwyd: (2019)
• Microvascular permeability during experimental human endotoxemia
  gan: van Eijk, L, et al.
  Cyhoeddwyd: (2004)