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Effect of the antihepcidin Spiegelmer lexaptepid on inflammation-induced decrease in serum iron in humans

Increased hepcidin production is key to the development of anemia of inflammation. We investigated whether lexaptepid, an antihepcidin l-oligoribonucleotide, prevents the decrease in serum iron during experimental human endotoxemia. This randomized, double-blind, placebo-controlled trial was carried...

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主要な著者: van Eijk, Lucas T., John, Aaron S. E., Schwoebel, Frank, Summo, Luciana, Vauléon, Stéphanie, Zöllner, Stefan, Laarakkers, Coby M., Kox, Matthijs, van der Hoeven, Johannes G., Swinkels, Dorine W., Riecke, Kai, Pickkers, Peter
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208279/
https://ncbi.nlm.nih.gov/pubmed/25163699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-03-559484
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