Short bioactive Spiegelmers to migraine-associated calcitonin gene-related peptide rapidly identified by a novel approach: Tailored-SELEX

We developed an integrated method to identify aptamers with only 10 fixed nucleotides through ligation and removal of primer binding sites within the systematic evolution of ligands by exponential enrichment (SELEX) process. This Tailored-SELEX approach was validated by identifying a Spiegelmer (‘mi...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Vater, Axel, Jarosch, Florian, Buchner, Klaus, Klussmann, Sven
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2003
Assuntos:	NAR Methods Online
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275487/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng130
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