Short bioactive Spiegelmers to migraine-associated calcitonin gene-related peptide rapidly identified by a novel approach: Tailored-SELEX

We developed an integrated method to identify aptamers with only 10 fixed nucleotides through ligation and removal of primer binding sites within the systematic evolution of ligands by exponential enrichment (SELEX) process. This Tailored-SELEX approach was validated by identifying a Spiegelmer (‘mi...

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Publié dans:	Nucleic Acids Res
Auteurs principaux:	Vater, Axel, Jarosch, Florian, Buchner, Klaus, Klussmann, Sven
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 2003
Sujets:	NAR Methods Online
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275487/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng130
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