Short bioactive Spiegelmers to migraine-associated calcitonin gene-related peptide rapidly identified by a novel approach: Tailored-SELEX

We developed an integrated method to identify aptamers with only 10 fixed nucleotides through ligation and removal of primer binding sites within the systematic evolution of ligands by exponential enrichment (SELEX) process. This Tailored-SELEX approach was validated by identifying a Spiegelmer (‘mi...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Vater, Axel, Jarosch, Florian, Buchner, Klaus, Klussmann, Sven
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 2003
Fag:	NAR Methods Online
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275487/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng130
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