Short bioactive Spiegelmers to migraine-associated calcitonin gene-related peptide rapidly identified by a novel approach: Tailored-SELEX

We developed an integrated method to identify aptamers with only 10 fixed nucleotides through ligation and removal of primer binding sites within the systematic evolution of ligands by exponential enrichment (SELEX) process. This Tailored-SELEX approach was validated by identifying a Spiegelmer (‘mi...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Vater, Axel, Jarosch, Florian, Buchner, Klaus, Klussmann, Sven
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 2003
Soggetti:	NAR Methods Online
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275487/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng130
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