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Synphilin-1A: An aggregation-prone isoform of synphilin-1 that causes neuronal death and is present in aggregates from α-synucleinopathy patients

α-Synucleinopathies are a group of neurological disorders characterized by the presence of intracellular inclusion bodies containing α-synuclein. We previously demonstrated that synphilin-1 interacts with α-synuclein, implying a role in Parkinson’s disease. We now report the identification and chara...

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Detalhes bibliográficos
Main Authors: Eyal, Allon, Szargel, Raymonde, Avraham, Eyal, Liani, Esti, Haskin, Joseph, Rott, Ruth, Engelender, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458673/
https://ncbi.nlm.nih.gov/pubmed/16595633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509707103
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