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A role of the double-stranded RNA-binding protein PACT in mouse ear development and hearing
To determine the physiological functions of the mammalian double-stranded RNA-binding protein PACT, the single-copy mouse Pact gene was disrupted and expression of the protein was completely ablated. The most notable phenotypes of the Pact(−/−) mouse were reduced size and severe microtia. As a resul...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458657/ https://ncbi.nlm.nih.gov/pubmed/16571658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601287103 |
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