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A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome

8-Oxoguanine (8-oxoG), a major spontaneous form of oxidative DNA damage, is considered to be a natural cause of genomic diversity in organisms because of its mutagenic potential. The steady-state level of 8-oxoG in the nuclear genome of a human cell has been estimated to be several residues per 10(6...

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Bibliografiset tiedot
Päätekijät: Ohno, Mizuki, Miura, Tomofumi, Furuichi, Masato, Tominaga, Yohei, Tsuchimoto, Daisuke, Sakumi, Kunihiko, Nakabeppu, Yusaku
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1457041/
https://ncbi.nlm.nih.gov/pubmed/16651663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.4769606
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