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Cleavage of the siRNA passenger strand during RISC assembly in human cells
A crucial step in the RNA interference (RNAi) pathway involves the assembly of RISC, the RNA-induced silencing complex. RISC initially recognizes a double-stranded short interfering RNA (siRNA), but only one strand is finally retained in the functional ribonucleoprotein complex. The non-incorporated...
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| Main Authors: | , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2006
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456892/ https://ncbi.nlm.nih.gov/pubmed/16439995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400637 |
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