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Negative Clonal Selection in Tumor Evolution

Development of cancer requires the acquisition of multiple oncogenic mutations and selection of the malignant clone. Cancer evolves within a finite host lifetime and mechanisms of carcinogenesis that accelerate this process may be more likely to contribute to the development of clinical cancers. Mut...

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Detalhes bibliográficos
Main Authors: Beckman, Robert A., Loeb, Lawrence A.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2005 by the Genetics Society of America 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456124/
https://ncbi.nlm.nih.gov/pubmed/16143627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.040840
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