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Clonal Interference in the Evolution of Influenza

The seasonal influenza A virus undergoes rapid evolution to escape human immune response. Adaptive changes occur primarily in antigenic epitopes, the antibody-binding domains of the viral hemagglutinin. This process involves recurrent selective sweeps, in which clusters of simultaneous nucleotide fi...

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Bibliografische gegevens
Hoofdauteurs: Strelkowa, Natalja, Lässig, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454888/
https://ncbi.nlm.nih.gov/pubmed/22851649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.143396
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