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Drug Resistance Evolution in HIV in the Late 1990s: Hard Sweeps, Soft Sweeps, Clonal Interference and the Accumulation of Drug Resistance Mutations

The evolution of drug resistance in pathogens such as HIV is an important and widely known example in the field of evolutionary medicine. Here, we focus on a unique data set from the late 1990s with multiple viral sequences from multiple time points in 118 patients. We study patterns of evolutionary...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Williams, Kadie-Ann, Pennings, Pleuni
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144074/
https://ncbi.nlm.nih.gov/pubmed/32075854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400772
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