Mechanism of origin unwinding: sequential binding of DnaA to double- and single-stranded DNA
The initiator protein DnaA of Escherichia coli binds to a 9mer consensus sequence, the DnaA box (5′-TT(A)/(T)TNCACA). If complexed with ATP it adopts a new binding specificity for a 6mer consensus sequence, the ATP-DnaA box (5′-AGatct). Using DNase footprinting and surface plasmon resonance we show...
Kaydedildi:
| Yayımlandı: | EMBO J |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2001
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145534/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11250912/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.6.1469 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|