The mitochondrial Hsp70-dependent import system actively unfolds preproteins and shortens the lag phase of translocation

Unfolding is an essential process during translocation of preproteins into mitochondria; however, controversy exists as to whether mitochondria play an active role in unfolding. We have established an in vitro system with a kinetic saturation of the mitochondrial import machinery, yielding transloca...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Lim, Joo Hyun, Martin, Falk, Guiard, Bernard, Pfanner, Nikolaus, Voos, Wolfgang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145481/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11230118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.5.941
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