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The mitochondrial Hsp70-dependent import system actively unfolds preproteins and shortens the lag phase of translocation

Unfolding is an essential process during translocation of preproteins into mitochondria; however, controversy exists as to whether mitochondria play an active role in unfolding. We have established an in vitro system with a kinetic saturation of the mitochondrial import machinery, yielding transloca...

詳細記述

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書誌詳細
主要な著者: Lim, Joo Hyun, Martin, Falk, Guiard, Bernard, Pfanner, Nikolaus, Voos, Wolfgang
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC145481/
https://ncbi.nlm.nih.gov/pubmed/11230118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.5.941
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