The mitochondrial Hsp70-dependent import system actively unfolds preproteins and shortens the lag phase of translocation

Unfolding is an essential process during translocation of preproteins into mitochondria; however, controversy exists as to whether mitochondria play an active role in unfolding. We have established an in vitro system with a kinetic saturation of the mitochondrial import machinery, yielding transloca...

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Bibliografische gegevens

Gepubliceerd in:	EMBO J
Hoofdauteurs:	Lim, Joo Hyun, Martin, Falk, Guiard, Bernard, Pfanner, Nikolaus, Voos, Wolfgang
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Nature Publishing Group 2001
Onderwerpen:	Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145481/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11230118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.5.941
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