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Mitochondrial GrpE modulates the function of matrix Hsp70 in translocation and maturation of preproteins.

Mitochondrial GrpE (Mge1p) is a mitochondrial cochaperone essential for viability of the yeast Saccharomyces cerevisiae. To study the role of Mge1p in the biogenesis of mitochondrial proteins, we isolated a conditional mutant allele of MGE1 which conferred a temperature-sensitive growth phenotype an...

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Bibliographic Details
Main Authors: Laloraya, S, Dekker, P J, Voos, W, Craig, E A, Pfanner, N
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC230965/
https://ncbi.nlm.nih.gov/pubmed/8524277
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