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Differential expression of IFN-α and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients
Loss of CD4(+) T cells, the hallmark of HIV pathogenesis, was suggested to be partly due to apoptosis. We recently reported that IFN-α produced by HIV-1-activated plasmacytoid dendritic cells (pDCs) contributes to CD4(+) T cell apoptosis by the TNF-related apoptosis-inducing ligand (TRAIL)/death rec...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1444883/ https://ncbi.nlm.nih.gov/pubmed/16632604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600363103 |
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