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Regulation of TNF-related apoptosis-inducing ligand on primary CD4(+) T cells by HIV-1: Role of type I IFN-producing plasmacytoid dendritic cells

TNF-related apoptosis-inducing ligand (TRAIL), a member of the TNF superfamily, was suggested to contribute to HIV-1 pathogenesis by inducing CD4(+) T cell death characteristic of AIDS. We previously reported HIV-1-mediated, TRAIL-induced apoptosis in primary CD4(+) T cells in vitro and observed ele...

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Detalhes bibliográficos
Main Authors: Herbeuval, Jean-Philippe, Hardy, Andrew W., Boasso, Adriano, Anderson, Stephanie A., Dolan, Matthew J., Dy, Michel, Shearer, Gene M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224361/
https://ncbi.nlm.nih.gov/pubmed/16174727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505251102
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