HIV inhibits CD4(+) T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells

Infection with the human immunodeficiency virus type-1 (HIV) results in acute and progressive numeric loss of CD4(+) T-helper cells and functional impairment of T-cell responses. The mechanistic basis of the functional impairment of the surviving cells is not clear. Indoleamine 2,3-dioxygenase (IDO)...

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Bibliografische gegevens
Hoofdauteurs: Boasso, Adriano, Herbeuval, Jean-Philippe, Hardy, Andrew W., Anderson, Stephanie A., Dolan, Matthew J., Fuchs, Dietmar, Shearer, Gene M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2007
Onderwerpen:
Immunobiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852248/
https://ncbi.nlm.nih.gov/pubmed/17158233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-034785
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