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Recombination of mitochondrial DNA detected in skeletal muscle of individuals with multiple mitochondrial DNA heteroplasmy

Experimental evidence for human mitochondrial DNA (mtDNA) recombination was recently obtained in one exceptional individual with paternal inheritance of mtDNA1 and in an in vitro cell culture system2. Whether mtDNA recombination is a common event in humans remained to be elucidated. To detect mtDNA...

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Detalhes bibliográficos
Main Authors: Zsurka, Gábor, Kraytsberg, Yevgenia, Kudina, Tatiana, Kornblum, Cornelia, Elger, Christian E., Khrapko, Konstantin, Kunz, Wolfram S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1444756/
https://ncbi.nlm.nih.gov/pubmed/16025113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1606
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