Associations of Peripheral Artery Disease With Calf Skeletal Muscle Mitochondrial DNA Heteroplasmy

BACKGROUND: Patients with peripheral artery disease (PAD) undergo frequent episodes of ischemia‐reperfusion in lower extremity muscles that may negatively affect mitochondrial health and are associated with impaired mobility. We hypothesized that skeletal muscle from PAD patients will show high mito...

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Veröffentlicht in:J Am Heart Assoc
Hauptverfasser: Gonzalez‐Freire, Marta, Moore, A. Zenobia, Peterson, Charlotte A., Kosmac, Kate, McDermott, Mary M., Sufit, Robert L., Guralnik, Jack M., Polonsky, Tamar, Tian, Lu, Kibbe, Melina R., Criqui, Michael H., Li, Lingyu, Leeuwenburgh, Christian, Ferrucci, Luigi
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428597/
https://ncbi.nlm.nih.gov/pubmed/32200714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.015197
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