Associations of Peripheral Artery Disease With Calf Skeletal Muscle Mitochondrial DNA Heteroplasmy

BACKGROUND: Patients with peripheral artery disease (PAD) undergo frequent episodes of ischemia‐reperfusion in lower extremity muscles that may negatively affect mitochondrial health and are associated with impaired mobility. We hypothesized that skeletal muscle from PAD patients will show high mito...

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Bibliografski detalji
Izdano u:J Am Heart Assoc
Glavni autori: Gonzalez‐Freire, Marta, Moore, A. Zenobia, Peterson, Charlotte A., Kosmac, Kate, McDermott, Mary M., Sufit, Robert L., Guralnik, Jack M., Polonsky, Tamar, Tian, Lu, Kibbe, Melina R., Criqui, Michael H., Li, Lingyu, Leeuwenburgh, Christian, Ferrucci, Luigi
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428597/
https://ncbi.nlm.nih.gov/pubmed/32200714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.015197
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