Associations of Peripheral Artery Disease With Calf Skeletal Muscle Mitochondrial DNA Heteroplasmy

BACKGROUND: Patients with peripheral artery disease (PAD) undergo frequent episodes of ischemia‐reperfusion in lower extremity muscles that may negatively affect mitochondrial health and are associated with impaired mobility. We hypothesized that skeletal muscle from PAD patients will show high mito...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Gonzalez‐Freire, Marta, Moore, A. Zenobia, Peterson, Charlotte A., Kosmac, Kate, McDermott, Mary M., Sufit, Robert L., Guralnik, Jack M., Polonsky, Tamar, Tian, Lu, Kibbe, Melina R., Criqui, Michael H., Li, Lingyu, Leeuwenburgh, Christian, Ferrucci, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428597/
https://ncbi.nlm.nih.gov/pubmed/32200714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.015197
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