Walking performance is positively correlated to calf muscle fiber size in peripheral artery disease subjects, but fibers show aberrant mitophagy: an observational study

BACKGROUND: Patients with lower extremity peripheral artery disease (PAD) have decreased mobility, which is not fully explained by impaired blood supply to the lower limb. Additionally, reports are conflicted regarding fiber type distribution patterns in PAD, but agree that skeletal muscle mitochond...

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Dettagli Bibliografici
Pubblicato in:J Transl Med
Autori principali: White, Sarah H., McDermott, Mary M., Sufit, Robert L., Kosmac, Kate, Bugg, Alex W., Gonzalez-Freire, Marta, Ferrucci, Luigi, Tian, Lu, Zhao, Lihui, Gao, Ying, Kibbe, Melina R., Criqui, Michael H., Leeuwenburgh, Christiaan, Peterson, Charlotte A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043620/
https://ncbi.nlm.nih.gov/pubmed/27687713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1030-6
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