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ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks
Ataxia-telangiectasia mutated (ATM), ataxia-telangiectasia Rad3-related (ATR) and the Mre11/Rad50/Nbs1 complex ensure genome stability in response to DNA damage. However, their essential role in DNA metabolism remains unknown. Here we show that ATM and ATR prevent accumulation of DNA double-strand b...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440833/ https://ncbi.nlm.nih.gov/pubmed/16601701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601045 |
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